The problem you are describing almost sounds more like a memory issue, considering when you say the CTDs are occurring, which are all more memory use intensive events. The problem you are having would not be fixed by save cleaners, and nor would they have been in original Skyrim - that is, as stated above, not what save cleaners do. If you removed scripted mods from ongoing game, then you will have to start a new game.' - Ilja That tool cleans obsolete entries and orphaned scripts from the game, but script data will remain in the save file, causing Papryus to constantly check it and creating errors. This includes work done with Save Script Cleaner. There is no such thing as a clean save, when mod is removed. Script cleaners are for when updating mods, NOT to fix broken/corrupted saves or to 'clean' saves after a mod or mods is disabled/uninstalled.

Because Obviously Bathesda are still being lazy ass's on their scripting and cleaning to such a point it now badly effects an unmodded game. I am wondering if there are any script cleaners and save game cleaning tools out there like TesVEdit was there for Skyrim. and since this seems to be getting worse and worse with each new game (I've had to start new games due to these bugs) Now for the OLD Skyrim I know this is normally down to mods and the needing of script cleaning or save game cleaning. walk forward and it will crash, some random NPC talks to me or around me and it will crash, I never know when or where it seems to happen VERY randomly. use an object (door, button, chain etc.) and it will crash, Talk to some random NPC to get or complete quest and it will crash. I could be fast traveling and it'll crash, be in the middle of combat and it will crash. (again I have NO mods installed yet as I'm going for the achievements and its a Clean reinstall of the game its self) So I'm doing my play though because I did notice a few quest changes in the game (small ones here and there and hell I even found some of the newer quests) But recently the game started CTDing on me for what seems like no reason. So here's the problem I have noticed that the game so far. I have tried the file verifying game to see if it needed repair it's done nothing.

(yes I uninstalled it for a while then reinstalled it a few days ago) so there should be NO broken/orphaned scripts from uninstalled mods, because this time around I haven't installed any yet (not even from Bathesda nets site or workshop) hell I haven't even used the console commands! Ok so I've just reinstalled SE after playing it with mods a WHILE ago.

Save game script cleaner sse